Apaise review: what are the brand's 4 supplements really worth?

What changed at Apaise in 2026

If you knew the brand before 2026, you will not recognise it. The old range was called Pic, Fond, Corps and La Nuit, mixed capsules and CBD gummies, and spoke a mass-market language. All of that is gone. Apaise rebuilt its catalogue around four numbered products, each tied to a single function, with a far more clinical visual identity and tone.

In practice, the ashwagandha became Cortisol Control [01], and the OptiPEA® product became Pain Regulation [03]. Two new references appeared, Deep Sleep [02] for sleep and Digest Flow for digestion. The anti-crisis gummies are no longer sold. If you were looking for an older product, it is normal that you can no longer find it.

Who is Apaise?

Apaise is a French supplement brand positioned on what it calls high-end nutraceuticals: few references, patented actives, high and published dosages. The catalogue deliberately holds four products, where many brands line up thirty. Each reference addresses one precise mechanism, from cortisol to inflammation by way of sleep and digestion.

📌 What the brand is built on:

• One named, patented lead active per product, never an anonymous blend.
• Dosages published item by item, in milligrams or in enzyme units.
• HPMC vegetable capsules, no additives, no fillers and no artificial flavourings.
• Vegan, gluten free and GMO free formulas, made in Europe to GMP standards.

The Apaise range in detail

Four single products, all sold in 60-capsule bottles for one month, except Pain Regulation which comes in 90 capsules. The brand also offers two-product bundles, priced below buying each separately.

• Cortisol Control [01], 34,90 €: Shoden® ashwagandha standardised to 35 % withanolides, 480 mg per daily dose. Two capsules in the evening with food.
• Deep Sleep [02], 34,90 €: melatonin 1.8 mg, GABA 400 mg, valerian 150 mg, passionflower 150 mg and tryptophan 200 mg. Two capsules 30 minutes before bed.
• Pain Regulation [03], 59,90 €: patented micronised OptiPEA® at 400 mg. Three capsules a day, one after each meal.
• Digest Flow, 34,90 €: DigeZyme® 200 mg, a five-enzyme complex patented by Sabinsa. One capsule before lunch and one before dinner.

Cortisol Control against a standard ashwagandha

This is the product where the gap with the market is easiest to measure, because withanolide content is an objective figure that can be compared from one brand to the next.

A closer look at the actives: what are these formulas really worth?

What the four products have in common is that the lead active is named. That sounds minor, but it is precisely what separates a verifiable formula from an unverifiable one. When a brand writes « enzyme complex 200 mg », nobody can judge. When it writes « DigeZyme® 200 mg, including amylase 4,800 U, protease 1,200 U, lipase 40 U, lactase 800 U, cellulase 220 U », the reader can compare.

On Cortisol Control, the 35 % withanolide content is the highest level available on the market today. The logical trade-off is a price above a standard root powder, which is consistent with the cost of the extract.

On Pain Regulation, the argument rests on micronisation. Generic PEA is poorly absorbed because its particles are too large; the micronised form of OptiPEA® targets exactly that. It is also the most expensive product in the range at 59,90 €, and the one that demands the most discipline with three doses a day.

On Digest Flow, one nuance is worth knowing: the clinical studies put forward relate to the DigeZyme® active and not to the finished product. That is common practice in the sector, but it deserves to be said. Note too that lipase is the least dosed enzyme in the formula, at 40 U against 4,800 U of amylase.

What to know before ordering

The brand sells directly only, on its own site. No pharmacy, no drugstore, no third-party reseller. That choice guarantees the product is genuine but rules out any price comparison.

Since the range was relaunched in 2026, the volume of verified customer reviews remains low. On products of this type, where individual response varies a great deal, that lack of track record is a real limitation to keep in mind.

Finally, the contraindications are not trivial. Cortisol Control and Digest Flow are not recommended during pregnancy and breastfeeding. Deep Sleep adds psychotropic treatments to that list. Pain Regulation calls for medical advice in case of immunosuppressant or anticoagulant treatment. If this applies to you, speak to a healthcare professional before ordering.